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The Medical Matchmaking Machine

Radiolab

Radiolab is on a curiosity bender. We ask deep questions and use investigative journalism to get the answers. A given episode might whirl you through science, legal history, and into the home of someone halfway across the world. The show is known for innovative sound design, smashing information into music. It is hosted by Lulu Miller and Latif Nasser.

As he finished his medical residency exam, David Fajgenbaum felt off.  He walked down to the ER and checked himself in.  Soon he was in the ICU with multiple organ failure.  The only drug for his condition didn’t work. He had months to live, if that.  If he was going to survive, he was going to have to find his own cure. Miraculously, he pulled it off in the nick of time. From that ordeal, he realized that our system of discovering and approving drugs is far from perfect, and that he might be able to use AI to find dozens, hundreds, even thousands of cures, hidden in plain sight, for as-yet untreatable diseases.  EPISODE CREDITS: Reported by - Latif Nasser Produced by - Maria Paz Gutiérrez with mixing help from - Jeremy S. Bloom Fact-checking by - Natalie A. Middleton EPISODE CITATIONS: Books - Blair Bigham, <a href="https://store.walrusmagazine.com/products/death-interrupted" target="_blank">Death Interrupted: How Modern Medicine is Complicating the Way We Die</a> Radiolab | Lateral Cuts: Check out <a href="https://radiolab.org/podcast/death-interrupted" target="_blank">Death Interrupted</a> (https://radiolab.org/podcast/death-interrupted), a conversation with Blair Bigham about a worldview shifting change of heart. <a href="https://radiolab.org/podcast/dirty-drug-and-ice-cream-tub">The Dirty Drug and the Ice Cream Tub</a> (<a href="https://radiolab.org/podcast/dirty-drug-and-ice-cream-tub">https://radiolab.org/podcast/dirty-drug-and-ice-cream-tub</a>) to hear the crazy story about how Rapamycin was discovered.Signup for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. <a href="https://radiolab.org/newsletter">Sign up</a> (https://radiolab.org/newsletter)!Radiolab is supported by listeners like you. Support Radiolab by becoming a member of <a href="http://members.radiolab.org">The Lab</a> (https://members.radiolab.org/) today.Follow our show on <a href="http://instagram.com/radiolab">Instagram</a>, <a href="http://twitter.com/radiolab">Twitter</a> and <a href="http://facebook.com/radiolab">Facebook</a> @radiolab, and share your thoughts with us by emailing <a href="mailto:radiolab@wnyc.org">radiolab@wnyc.org</a>. Leadership support for Radiolab’s science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.

As he finished his medical school exam, David Fajgenbaum felt off.  He walked down to the ER and checked himself in.  Soon he was in the ICU with multiple organ failure.  The only drug for his condition didn’t work. He had months to live, if that.  If he was going to survive, he was going to have to find his own cure. Miraculously, he pulled it off in the nick of time. From that ordeal, he realized that our system of discovering and approving drugs is far from perfect, and that he might be able to use AI to find dozens, hundreds, even thousands of cures, hidden in plain sight, for as-yet untreatable diseases.  EPISODE CREDITS: Reported by - Latif Nasser Produced by - Maria Paz Gutiérrez with mixing help from - Jeremy S. Bloom Fact-checking by - Natalie A. Middleton VISIT: <a href="http://everycure.org" target="_blank">Everycure.org</a> (<a href="https://www.everycure.org">https://www.everycure.org</a>) EPISODE CITATIONS: Books - Blair Bigham - <a href="https://store.walrusmagazine.com/products/death-interrupted"> Death Interrupted: How Modern Medicine is Complicating the Way We Die</a>David Fajgenbaum - <a href="https://www.penguinrandomhouse.com/books/567298/chasing-my-cure-by-david-fajgenbaum/">Chasing My Cure</a>, (<a href="https://url.us.m.mimecastprotect.com/s/wQYvCqxrKVCn3vKYtQiPsEHEVd?domain=davidfajgenbaum.com/" target="_blank">https://davidfajgenbaum.com/</a>)Radiolab | Lateral Cuts: Check out <a href="https://radiolab.org/podcast/death-interrupted">Death Interrupted </a>(<a href="https://radiolab.org/podcast/death-interrupted" target="_blank">https://radiolab.org/podcast/death-interrupted</a>), a conversation with Blair Bigham about a worldview shifting change of heart. <a href="https://radiolab.org/podcast/dirty-drug-and-ice-cream-tub">The Dirty Drug and the Ice Cream Tub</a> (<a href="https://radiolab.org/podcast/dirty-drug-and-ice-cream-tub">https://radiolab.org/podcast/dirty-drug-and-ice-cream-tub</a>) to hear the crazy story about how Rapamycin was discovered.Signup for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. <a href="https://radiolab.org/newsletter">Sign up</a> (https://radiolab.org/newsletter)!Radiolab is supported by listeners like you. Support Radiolab by becoming a member of <a href="http://members.radiolab.org">The Lab</a> (https://members.radiolab.org/) today.Follow our show on <a href="http://instagram.com/radiolab">Instagram</a>, <a href="http://twitter.com/radiolab">Twitter</a> and <a href="http://facebook.com/radiolab">Facebook</a> @radiolab, and share your thoughts with us by emailing <a href="mailto:radiolab@wnyc.org">radiolab@wnyc.org</a>. Leadership support for Radiolab’s science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
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