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How Dopamine & Serotonin Shape Decisions, Motivation & Learning | Dr. Read Montague

Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. 
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

Dr. Read Montague, PhD, is a professor and director of the Center for Human Neuroscience Research at Virginia Tech and an expert in how dopamine and serotonin shape human learning, motivation and decision-making. We discuss how they impact focused effort in the context of short- and long-term goals of all kinds. Also, how SSRIs and low-effort, high-engagement activities reduce the rewarding properties of dopamine, and how AI algorithms are revolutionizing understanding of the brain.

Episode show notes are available at hubermanlab.com.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

David: https://davidprotein.com/huberman

Joovv: https://joovv.com/huberman

Function: https://functionhealth.com/huberman

LMNT: https://drinklmnt.com/huberman

Timestamps

(00:00:00) Read Montague

(00:02:54) Dopamine, Motivation & Learning

(00:08:49) Reward Prediction Error, Expectations

(00:12:24) Sponsors: David & Joovv

(00:14:54) Foraging, Dating, Expectations vs Outcomes; AI

(00:23:36) Dopamine, Expectation, Motivation; Forward Drive; Dopamine "Hits"

(00:29:58) Baseline Dopamine & Fluctuations; Parkinson's Disease

(00:34:36) Movement, Urgency; ADHD, Bee's Dance, Explorer vs Focus Mode

(00:42:29) Sponsor: AG1

(00:43:40) Social Media, ADHD; Explorers vs Task-Based, Combat

(00:50:54) Effort, Learning; Social Media & Phones, Resisting Behaviors

(01:01:36) Serotonin & Dopamine, Opponency, SSRIs

(01:11:21) Hunger, Dopamine; Negative Feedback, Learning, Trauma; Torture

(01:18:34) Drugs of Abuse & High Dopamine

(01:19:48) Sponsor: Function

(01:21:35) Trauma & Dopamine Adaptation

(01:27:34) SSRIs, Dopamine, Positive Experiences

(01:29:50) Deep Brain Stimulation; Measuring Dopamine & Serotonin in Humans

(01:36:16) Sleep; Divorce; Science is a Contact Sport

(01:45:14) Long-Term Motivation, Learning How to Fail, Tool: Kids & Sports

(01:54:14) Sponsor: LMNT

(01:55:34) Meditation, Breathing, Learning; Dopamine as a Currency

(02:04:38) Function of Sleep, Motivation; Time Perception & Dopamine, Tracking Time

(02:13:18) LLMs, AI, Uses & Problem Solving

(02:18:33) Future Projects, Commercial Brain-Machine Interfaces; Concentration

(02:25:57) Dopamine "Hits"?; Depression & Schizophrenia; Quitting

(02:30:17) Dopamine & Serotonin Misunderstandings; Internal Satisfaction; Motivation

(02:35:58) Serotonin Syndrome; Acknowledgements

(02:38:31) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures
Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Read Montague, PhD, is a professor and director of the Center for Human Neuroscience Research at Virginia Tech’s Fralin Biomedical Research Institute and an expert in how dopamine and serotonin shape human learning, motivation and decision-making. We discuss how they impact focused effort in the context of short- and long-term goals of all kinds. Also, how SSRIs and low-effort, high-engagement activities reduce the rewarding properties of dopamine, and how AI algorithms are revolutionizing understanding of the brain.

Episode show notes are available at hubermanlab.com.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

David: https://davidprotein.com/huberman

Joovv: https://joovv.com/huberman

Function: https://functionhealth.com/huberman

LMNT: https://drinklmnt.com/huberman

Timestamps

(00:00:00) Read Montague

(00:02:54) Dopamine, Motivation & Learning

(00:08:49) Reward Prediction Error, Expectations

(00:12:24) Sponsors: David & Joovv

(00:14:54) Foraging, Dating, Expectations vs Outcomes; AI

(00:23:36) Dopamine, Expectation, Motivation; Forward Drive; Dopamine "Hits"

(00:29:58) Baseline Dopamine & Fluctuations; Parkinson's Disease

(00:34:36) Movement, Urgency; ADHD, Bee's Dance, Explorer vs Focus Mode

(00:42:29) Sponsor: AG1

(00:43:40) Social Media, ADHD; Explorers vs Task-Based, Combat

(00:50:54) Effort, Learning; Social Media & Phones, Resisting Behaviors

(01:01:36) Serotonin & Dopamine, Opponency, SSRIs

(01:11:21) Hunger, Dopamine; Negative Feedback, Learning, Trauma; Torture

(01:18:34) Drugs of Abuse & High Dopamine

(01:19:48) Sponsor: Function

(01:21:35) Trauma & Dopamine Adaptation

(01:27:34) SSRIs, Dopamine, Positive Experiences

(01:29:50) Deep Brain Stimulation; Measuring Dopamine & Serotonin in Humans

(01:36:16) Sleep; Divorce; Science is a Contact Sport

(01:45:14) Long-Term Motivation, Learning How to Fail, Tool: Kids & Sports

(01:54:14) Sponsor: LMNT

(01:55:34) Meditation, Breathing, Learning; Dopamine as a Currency

(02:04:38) Function of Sleep, Motivation; Time Perception & Dopamine, Tracking Time

(02:13:18) LLMs, AI, Uses & Problem Solving

(02:18:33) Future Projects, Commercial Brain-Machine Interfaces; Concentration

(02:25:57) Dopamine "Hits"?; Depression & Schizophrenia; Quitting

(02:30:17) Dopamine & Serotonin Misunderstandings; Internal Satisfaction; Motivation

(02:35:58) Serotonin Syndrome; Acknowledgements

(02:38:31) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures
Learn more about your ad choices. Visit megaphone.fm/adchoices

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