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GUEST SERIES | Dr. Andy Galpin: Optimal Protocols to Build Strength & Grow Muscles

Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. 
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

In this episode 2 of a 6-part special series, Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton and world expert on exercise science, explains optimal protocols for increasing strength and causing hypertrophy (muscle growth), as well as for increasing speed and power. He explains the training principles and underlying mechanisms for reaching these goals. Our conversation covers a breadth of training topics, including selecting the number of repetitions, sets, inter-set and inter-workout rest periods, warm-ups, exercise cadence, breathing, stretching, recovery, training frequency, overcoming plateaus, nutrition, and he gives specific examples of exercises for power, strength, and hypertrophy.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Eight Sleep: https://eightsleep.com/huberman
Levels: https://levels.link/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Benefits of Strength & Hypertrophy Training, Aging
(00:10:52) Strength & Hypertrophy Training, Aesthetics 
(00:14:02) Sponsors: Eight Sleep, Levels
(00:17:48) Strength vs. Hypertrophy Training: Adaptations
(00:22:42) Ligaments, Tendons & Resistance Training
(00:28:05) Bone Strength & Resistance Training, Age, Women
(00:32:38) Strength Training & Major Adaptations
(00:41:32) Sponsor: AG1 
(00:42:25) Hypertrophy Training & Major Adaptations; Protein Synthesis
(00:45:56) Endurance vs. Strength Training & Cell Signaling, Protein Synthesis
(00:52:26) Muscle Hypertrophy, Sarcoplasmic Hypertrophy
(00:56:37) Muscle Physiology & Plasticity, Muscle “Memory”
(01:04:00) Non-Negotiables & Modifiable Variables of Exercise Training
(01:11:51) Sponsor: InsideTracker
(01:12:53) Tool: Speed & Power Training, “3 to 5” Approach, Periodization, Planning 
(01:22:02) Warming Up & Training, Dynamic Movements
(01:30:55) Strength vs. Hypertrophy Repetition Cadence, Triphasic Training
(01:44:03) Tool: Breathing & Training, Valsalva Technique
(01:53:22) Tool: Training Auto-Regulation, Specificity vs. Variation, Prilepin's Chart
(02:02:35) Training to Failure, Exercise Selection & Recovery, Standardization
(02:13:45) Tool: Power vs. Strength Training & Modifiable Variables; Supersets 
(02:24:22) Sets & Rest Periods; Stretching
(02:28:48) Tools: Power Training & Modifiable Variables; Examples
(02:30:16) Tools: Strength Training & Modifiable Variables, Cluster Sets, Dynamic Variable Sets
(02:40:44) Power & Strength Training Protocols
(02:43:37) Intention, Focus & Exercise
(02:47:29) Hypertrophy Training Program, Muscle Growth & Signaling 
(02:55:12) Tools: Hypertrophy Training & Modifiable Variables; Examples
(03:03:02) Balanced Muscle Development & Hypertrophy
(03:09:04) Tools: Hypertrophy Training & Modifiable Variables; Splits
(03:23:08) “Non-Responders” & Exercise Plateaus, Volume
(03:27:06) Hypertrophy, Repetition & Rest Ranges, Muscle Failure, “Chaos Management”
(03:37:39) Frequency & Workout Duration, Splits
(03:44:52) Training Frequency, Infrequent Training, Intermediate Repetition Ranges
(03:55:22) Hypertrophy, Muscle Damage & Recovery
(04:01:15) Combining Cardiovascular & Hypertrophy Training, Interference Effect
(04:06:22) Hypertrophy Training Protocols 
(04:12:06) Tool: Neck & Rear Deltoid Exercises, Stabilization & Hypertrophy
(04:14:42) Hypertrophy: Reps, Sets & Progression, “Hidden” Stressors, Exercises to Avoid
(04:21:09) Deliberate Cold Exposure & Hypertrophy vs. Strength
(04:26:41) Nutrition, Timing & Strength/Hypertrophy; Creatine
(04:38:04) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

In this episode 2 of a 6-part special series, Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton and world expert on exercise science, explains optimal protocols for increasing strength and causing hypertrophy (muscle growth), as well as for increasing speed and power. He explains the training principles and underlying mechanisms for reaching these goals. Our conversation covers a breadth of training topics, including selecting the number of repetitions, sets, inter-set and inter-workout rest periods, warm-ups, exercise cadence, breathing, stretching, recovery, training frequency, overcoming plateaus, nutrition, and he gives specific examples of exercises for power, strength, and hypertrophy.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Eight Sleep: https://eightsleep.com/huberman
Levels: https://levels.link/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Benefits of Strength & Hypertrophy Training, Aging
(00:10:52) Strength & Hypertrophy Training, Aesthetics 
(00:14:02) Sponsors: Eight Sleep, Levels
(00:17:48) Strength vs. Hypertrophy Training: Adaptations
(00:22:42) Ligaments, Tendons & Resistance Training
(00:28:05) Bone Strength & Resistance Training, Age, Women
(00:32:38) Strength Training & Major Adaptations
(00:41:32) Sponsor: AG1 
(00:42:25) Hypertrophy Training & Major Adaptations; Protein Synthesis
(00:45:56) Endurance vs. Strength Training & Cell Signaling, Protein Synthesis
(00:52:26) Muscle Hypertrophy, Sarcoplasmic Hypertrophy
(00:56:37) Muscle Physiology & Plasticity, Muscle “Memory”
(01:04:00) Non-Negotiables & Modifiable Variables of Exercise Training
(01:11:51) Sponsor: InsideTracker
(01:12:53) Tool: Speed & Power Training, “3 to 5” Approach, Periodization, Planning 
(01:22:02) Warming Up & Training, Dynamic Movements
(01:30:55) Strength vs. Hypertrophy Repetition Cadence, Triphasic Training
(01:44:03) Tool: Breathing & Training, Valsalva Technique
(01:53:22) Tool: Training Auto-Regulation, Specificity vs. Variation, Prilepin's Chart
(02:02:35) Training to Failure, Exercise Selection & Recovery, Standardization
(02:13:45) Tool: Power vs. Strength Training & Modifiable Variables; Supersets 
(02:24:22) Sets & Rest Periods; Stretching
(02:28:48) Tools: Power Training & Modifiable Variables; Examples
(02:30:16) Tools: Strength Training & Modifiable Variables, Cluster Sets, Dynamic Variable Sets
(02:40:44) Power & Strength Training Protocols
(02:43:37) Intention, Focus & Exercise
(02:47:29) Hypertrophy Training Program, Muscle Growth & Signaling 
(02:55:12) Tools: Hypertrophy Training & Modifiable Variables; Examples
(03:03:02) Balanced Muscle Development & Hypertrophy
(03:09:04) Tools: Hypertrophy Training & Modifiable Variables; Splits
(03:23:08) “Non-Responders” & Exercise Plateaus, Volume
(03:27:06) Hypertrophy, Repetition & Rest Ranges, Muscle Failure, “Chaos Management”
(03:37:39) Frequency & Workout Duration, Splits
(03:44:52) Training Frequency, Infrequent Training, Intermediate Repetition Ranges
(03:55:22) Hypertrophy, Muscle Damage & Recovery
(04:01:15) Combining Cardiovascular & Hypertrophy Training, Interference Effect
(04:06:22) Hypertrophy Training Protocols 
(04:12:06) Tool: Neck & Rear Deltoid Exercises, Stabilization & Hypertrophy
(04:14:42) Hypertrophy: Reps, Sets & Progression, “Hidden” Stressors, Exercises to Avoid
(04:21:09) Deliberate Cold Exposure & Hypertrophy vs. Strength
(04:26:41) Nutrition, Timing & Strength/Hypertrophy; Creatine
(04:38:04) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer
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