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Essentials: Understanding & Healing the Mind | Dr. Karl Deisseroth

Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. 
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

In this episode of Huberman Lab Essentials, my guest is Dr. Karl Deisseroth, M.D., Ph.D., a clinical psychiatrist and professor of bioengineering and of psychiatry and behavioral sciences at Stanford University.

We discuss his experiences as a clinician treating complex psychiatric conditions and his lab’s pioneering work in developing transformative therapies for mental illness. He explains the complexities of mental illness and how emerging technologies—such as optogenetics and brain-machine interfaces—could revolutionize care. We also explore promising new therapies, including psychedelics and MDMA, for conditions like depression and PTSD.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

David: https://davidprotein.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Timestamps

00:00:00 Karl Deisseroth; Neurology vs Psychiatry

00:01:36 Speech; Blood Test?; Seeking Help

00:04:20 Feelings, Jargon; Psychiatric Treatment

00:09:40 Sponsor: David

00:10:55 Future Treatment; Vagus Nerve Stimulation, Depression, Optogenetics

00:19:40 Brain-Machine Interfaces

00:20:53 Sponsor: Eight Sleep

00:23:00 ADHD Symptoms, Lifestyle, Technology

00:29:34 Psychedelics, Depression Treatment, Risks

00:35:43 Sponsor: AG1

00:37:30 MDMA (Ecstasy), Trauma & Post-Traumatic Stress Disorder (PTSD) Treatment

00:40:33 Projections: A Story of Human Emotions Book, Optimism

Disclaimer & Disclosures

In this episode of Huberman Lab Essentials, my guest is Dr. Karl Deisseroth, M.D., Ph.D., a clinical psychiatrist and professor of bioengineering and of psychiatry and behavioral sciences at Stanford University.

We discuss his experiences as a clinician treating complex psychiatric conditions and his lab’s pioneering work in developing transformative therapies for mental illness. He explains the complexities of mental illness and how emerging technologies—such as optogenetics and brain-machine interfaces—could revolutionize care. We also explore promising new therapies, including psychedelics and MDMA, for conditions like depression and PTSD.

Read the episode show notes at hubermanlab.com.

Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch or listen to the full-length episode at ⁠hubermanlab.com⁠.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

David: https://davidprotein.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Timestamps

00:00:00 Karl Deisseroth; Neurology vs Psychiatry

00:01:36 Speech; Blood Test?; Seeking Help

00:04:20 Feelings, Jargon; Psychiatric Treatment

00:09:40 Sponsor: David

00:10:55 Future Treatment; Vagus Nerve Stimulation, Depression, Optogenetics

00:19:40 Brain-Machine Interfaces

00:20:53 Sponsor: Eight Sleep

00:23:00 ADHD Symptoms, Lifestyle, Technology

00:29:34 Psychedelics, Depression Treatment, Risks

00:35:43 Sponsor: AG1

00:37:30 MDMA (Ecstasy), Trauma & Post-Traumatic Stress Disorder (PTSD) Treatment

00:40:33 Projections: A Story of Human Emotions Book, Optimism

Disclaimer & Disclosures
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