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Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. 
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

In loving memory of Nolan Williams (1982-2025): ⁠https://stan.md/3Qle2zp⁠

In this Huberman Lab Essentials episode, my guest is Dr. Nolan Williams, MD, a triple board-certified psychiatrist and neurologist. We discuss cutting-edge treatments for depression and post-traumatic stress disorder (PTSD), including transcranial magnetic stimulation, neuromodulation, and psychedelic-assisted therapies. We also discuss the neurobiology and therapeutic potential of specific psychedelic compounds, including psilocybin, MDMA, ibogaine, and ayahuasca.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Function: https://functionhealth.com/huberman

BetterHelp: https://betterhelp.com/huberman

Timestamps

(00:00:00) Nolan Williams

(00:00:21) Depression

(00:02:45) Heart & Mind Connection, Transcranial Magnetic Stimulation (TMS)

(00:05:15) TMS for Depression

(00:07:47) Sponsor: Function

(00:09:24) SSRIs & Chemical imbalance, TMS, Psychedelics

(00:15:24) Psilocybin, MDMA, Trauma

(00:18:21) MDMA Clinical Trials & PTSD; Psilocybin & Depression

(00:20:18) Sponsor: BetterHelp

(00:21:38) Psilocybin, Brain Connectivity & Depression

(00:23:59) Ibogaine, Empathy; Psychedelic Breakthrough & Risk

(00:30:36) Ayahuasca, Behavior Change, Prisoners

(00:34:46) Sponsor: AG1

(00:36:05) Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT)

(00:40:07) Acknowledgements

Disclaimer & Disclosures
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Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

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