Essentials: How Hormones Shape Sexual Development
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13. 2. 2025
44 min
In this Huberman Lab Essentials episode, I explain the crucial role hormones play in shaping the sexual development of both the brain and body.
I discuss how biological masculinization and feminization depend on factors such as genetics, hormone ratios, and receptor availability. I also explore how hormones like testosterone, estrogen, and other steroid hormones influence sexual characteristics and brain development. Additionally, I examine the impact of environmental factors—such as herbicides like atrazine, cannabis, alcohol, and even cell phones—on hormone function and reproductive health.
Huberman Lab Essentials are short episodes (approximately 30 minutes) focused on key science and protocol takeaways from past Huberman Lab episodes. Essentials are released every Thursday, while full-length episodes continue to be released every Monday.
Read the full episode show notes, including referenced articles, resources, and people mentioned at hubermanlab.com.
This Huberman Lab Essentials episode is from the full-length episode, available here: https://go.hubermanlab.com/PQYuc9i
Thank you to our sponsors
AG1: https://drinkag1.com/huberman
Function: https://functionhealth.com/huberman
Our Place: https://fromourplace.com/huberman
BetterHelp: https://betterhelp.com/huberman
Timestamps
00:00:00 Huberman Lab Essentials; Hormones, Sexual Development
00:01:25 Chromosomal Sex, Gonadal Sex, Hormonal Sex, Morphology
00:06:08 Sponsor: Function
00:07:56 Steroid Hormones, Sexual Characteristics
00:10:59 Primary & Secondary Sexual Characteristics, Dihydrotestosterone (DHT), Kisspeptin
00:15:12 Masculinization of Brain, Estrogen
00:16:29 Sponsors: Our Place, BetterHelp
00:19:15 Herbicides, Atrazine, Hormone Effects, Sperm Counts
00:25:04 Female Sexual Development, Androgen Insensitivity Syndrome
00:28:37 Sponsor: AG1
00:29:41 Cannabis & Aromatase Activity, Gynecomastia; Alcohol & Estrogen Activity
00:32:34 Cell Phones & Gonads
00:35:24 Beard & Hair Growth, DHT
00:38:42 Hyenas, Hormones, Androstenedione; Plants
00:43:44 Recap & Key Takeaways
Disclaimer & Disclosures
Popis podcastu
The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017.
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.