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Tools to Reduce & Manage Pain | Dr. Sean Mackey

Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. 
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

In this episode, my guest is Dr. Sean Mackey, M.D., Ph.D., Chief of the Division of Pain Medicine and Professor of Anesthesiology, Perioperative and Pain Medicine and Neurology at Stanford University School of Medicine. His clinical and research efforts focus on using advanced neurosciences, patient outcomes, biomarkers and informatics to treat pain.
We discuss what pain is at the level of the body and mind, pain thresholds, and the various causes of pain. We also discuss effective protocols for controlling and reducing pain, including the use of heat and cold, acupuncture, chiropractic, physical therapy, nutrition, and supplementation.
We also discuss how pain is influenced by our emotions, stress and memories, and practical tools to control one’s psychological perception of pain.
And we discuss pain medications, including the controversial use of opioids and the opioid crisis.
This episode will help people understand, manage, and control their pain as well as the pain of others.
For show notes, including referenced articles and additional resources, please visit hubermanlab.com.
Thank you to our sponsors
AG1: https://drinkag1.com/huberman
AeroPress: https://aeropress.com/huberman
Levels: https://levels.link/huberman
BetterHelp: https://betterhelp.com/huberman
InsideTracker: https://insidetracker.com/huberman
Momentous: https://livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Sean Mackey
(00:02:11) Sponsors: AeroPress, Levels & BetterHelp
(00:06:13) Pain, Unique Experiences, Chronic Pain
(00:13:05) Pain & the Brain
(00:16:15) Treating Pain, Medications: NSAIDs & Analgesics
(00:22:46) Inflammation, Pain & Recovery; Ibuprofen, Naprosyn & Aspirin
(00:28:51) Sponsor: AG1
(00:30:19) Caffeine, NSAIDs, Tylenol
(00:32:34) Pain & Touch, Gate Control Theory
(00:38:56) Pain Threshold, Gender
(00:44:53) Pain in Children, Pain Modulation (Pain Inhibits Pain)
(00:53:20) Tool: Heat, Cold & Pain; Changing Pain Threshold
(00:59:53) Sponsor: InsideTracker
(01:00:54) Tools: Psychology, Mindfulness-Based Stress Reduction, Catastrophizing
(01:08:29) Tool: Hurt vs. Harmed?, Chronic Pain
(01:12:38) Emotional Pain, Anger, Medication
(01:20:43) Tool: Nutrition & Pain; Food Sensitization & Elimination Diets
(01:28:45) Visceral Pain; Back, Chest & Abdominal Pain
(01:34:02) Referenced Pain, Neuropathic Pain; Stress, Memory & Psychological Pain
(01:40:23) Romantic Love & Pain, Addiction
(01:48:57) Endogenous & Exogenous Opioids, Morphine
(01:53:17) Opioid Crisis, Prescribing Physicians
(02:02:21) Opioids & Fentanyl; Morphine, Oxycontin, Methadone
(02:07:44) Kratom, Cannabis, CBD & Pain; Drug Schedules
(02:18:12) Pain Management Therapies, Acupuncture
(02:22:19) Finding Reliable Physicians, Acupuncturist
(02:26:36) Chiropractic & Pain Treatment; Chronic Pain & Activity
(02:31:35) Physical Therapy & Chronic Pain; Tool: Pacing
(02:36:35) Supplements: Acetyl-L-Carnitine, Alpha Lipoic Acid, Vitamin C, Creatine
(02:42:25) Pain Management, Cognitive Behavioral Therapy (CBT), Biofeedback
(02:48:32) National Pain Strategy, National Pain Care Act
(02:54:05) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter
Disclaimer

In this episode, my guest is Dr. Sean Mackey, M.D., Ph.D., Chief of the Division of Pain Medicine and Professor of Anesthesiology, Perioperative and Pain Medicine and Neurology at Stanford University School of Medicine. His clinical and research efforts focus on using advanced neurosciences, patient outcomes, biomarkers and informatics to treat pain.
We discuss what pain is at the level of the body and mind, pain thresholds, and the various causes of pain. We also discuss effective protocols for controlling and reducing pain, including the use of heat and cold, acupuncture, chiropractic, physical therapy, nutrition, and supplementation.
We also discuss how pain is influenced by our emotions, stress and memories, and practical tools to control one’s psychological perception of pain.
And we discuss pain medications, including the controversial use of opioids and the opioid crisis.
This episode will help people understand, manage, and control their pain as well as the pain of others.
For show notes, including referenced articles and additional resources, please visit hubermanlab.com.
Use Ask Huberman Lab, our new AI-powered platform, for a summary, clips, and insights from this episode.
Thank you to our sponsors
AG1: https://drinkag1.com/huberman
LMNT: https://drinklmnt.com/hubermanlab
Waking Up: https://wakingup.com/huberman
Momentous: https://livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Sean Mackey
(00:02:28) Sponsors: LMNT & Waking Up
(00:06:13) Pain, Unique Experiences, Chronic Pain
(00:13:05) Pain & the Brain
(00:16:15) Treating Pain, Medications: NSAIDs & Analgesics
(00:22:46) Inflammation, Pain & Recovery; Ibuprofen, Naprosyn & Aspirin
(00:27:51) Sponsor: AG1
(00:30:19) Caffeine, NSAIDs, Tylenol
(00:32:34) Pain & Touch, Gate Control Theory
(00:38:56) Pain Threshold, Gender
(00:44:53) Pain in Children, Pain Modulation (Pain Inhibits Pain)
(00:53:20) Tool: Heat, Cold & Pain; Changing Pain Threshold
(01:00:54) Tools: Psychology, Mindfulness-Based Stress Reduction, Catastrophizing
(01:08:29) Tool: Hurt vs. Harmed?, Chronic Pain
(01:12:38) Emotional Pain, Anger, Medication
(01:20:43) Tool: Nutrition & Pain; Food Sensitization & Elimination Diets
(01:28:45) Visceral Pain; Back, Chest & Abdominal Pain
(01:34:02) Referenced Pain, Neuropathic Pain; Stress, Memory & Psychological Pain
(01:40:23) Romantic Love & Pain, Addiction
(01:48:57) Endogenous & Exogenous Opioids, Morphine
(01:53:17) Opioid Crisis, Prescribing Physicians
(02:02:21) Opioids & Fentanyl; Morphine, Oxycontin, Methadone
(02:07:44) Kratom, Cannabis, CBD & Pain; Drug Schedules
(02:18:12) Pain Management Therapies, Acupuncture
(02:22:19) Finding Reliable Physicians, Acupuncturist
(02:26:36) Chiropractic & Pain Treatment; Chronic Pain & Activity
(02:31:35) Physical Therapy & Chronic Pain; Tool: Pacing
(02:36:35) Supplements: Acetyl-L-Carnitine, Alpha Lipoic Acid, Vitamin C, Creatine
(02:42:25) Pain Management, Cognitive Behavioral Therapy (CBT), Biofeedback
(02:48:32) National Pain Strategy, National Pain Care Act
(02:54:05) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter
Disclaimer
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Tools to Reduce & Manage Pain | Dr. Sean Mackey

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