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How Smells Influence Our Hormones, Health & Behavior | Dr. Noam Sobel

Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. 
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

In this episode, my guest is Noam Sobel, PhD, professor of neurobiology in the department of brain sciences at the Weizmann Institute of Science. Dr. Sobel explains his lab’s research on the biological mechanisms of smell (“olfaction”) and how sensing odorants and chemicals in our environment impacts human behavior, cognition, social connections, and hormones. He explains how smell is a crucial component of “social sensing” and how we use olfaction when meeting new people to determine things about their physiology and psychology, and he explains how this impacts friendships and romantic partners. He explains how smell influences emotions, hormone levels, memories and the relationship between breathing and autonomic homeostasis. He describes how smell-based screening tests can aid disease diagnosis and explains his lab’s work on digitization of smell — which may soon allow online communication to include “sending of odors” via the internet. Dr. Sobel’s work illustrates how sensitive human olfaction is and how it drives much of our biology and behavior.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
LMNT: https://drinklmnt.com/huberman
Waking Up: https://www.wakingup.com/huberman
Momentous: https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Noam Sobel
(00:04:03) Sponsors: LMNT & Waking Up
(00:06:46) Olfaction Circuits (Smell)
(00:14:49) Loss & Regeneration of Smell, Illness
(00:21:39) Brain Processing of Smell
(00:24:40) Smell & Memories
(00:25:11) Sponsor: AG1
(00:29:07) Humans & Odor Tracking
(00:39:25) The Alternating Nasal Cycle & Autonomic Nervous System
(00:48:18) Cognitive Processing & Breathing
(00:54:47) Neurodegenerative Diseases & Olfaction
(01:00:12) Congenital Anosmia
(01:06:19) Handshaking, Sharing Chemicals & Social Sensing
(01:15:07) Smelling Ourselves & Smelling Others
(01:22:02) Odors & Romantic Attraction
(01:24:58) Vomeronasal Organ, “Bruce Effect” & Miscarriage
(01:40:20) Social Chemo-Signals, Fear
(01:50:26) Chemo-Signaling, Aggression & Offspring
(02:03:57) Menstrual Cycle Synchronization
(02:12:11) Sweat, Tears, Emotions & Testosterone
(02:27:46) Science Politics
(02:37:54) Food Odors & Nutritional Value
(02:45:34) Human Perception & Odorant Similarity
(02:52:12) Digitizing Smell, COVID-19 & Smell
(03:05:50) Medical Diagnostic Future & Olfaction Digitization
(03:10:55) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

In this episode, my guest is Noam Sobel, PhD, professor of neurobiology in the department of brain sciences at the Weizmann Institute of Science. Dr. Sobel explains his lab’s research on the biological mechanisms of smell (“olfaction”) and how sensing odorants and chemicals in our environment impacts human behavior, cognition, social connections, and hormones. He explains how smell is a crucial component of “social sensing” and how we use olfaction when meeting new people to determine things about their physiology and psychology, and he explains how this impacts friendships and romantic partners. He explains how smell influences emotions, hormone levels, memories and the relationship between breathing and autonomic homeostasis. He describes how smell-based screening tests can aid disease diagnosis and explains his lab’s work on digitization of smell — which may soon allow online communication to include “sending of odors” via the internet. Dr. Sobel’s work illustrates how sensitive human olfaction is and how it drives much of our biology and behavior.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1: https://athleticgreens.com/huberman
LMNT: https://drinklmnt.com/hubermanlab
Waking Up: https://wakingup.com/huberman
Momentous: https://livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Noam Sobel
(00:04:03) Sponsors: LMNT & Waking Up
(00:06:46) Olfaction Circuits (Smell)
(00:14:49) Loss & Regeneration of Smell, Illness
(00:21:39) Brain Processing of Smell
(00:24:40) Smell & Memories
(00:25:11) Sponsor: AG1
(00:29:07) Humans & Odor Tracking
(00:39:25) The Alternating Nasal Cycle & Autonomic Nervous System
(00:48:18) Cognitive Processing & Breathing
(00:54:47) Neurodegenerative Diseases & Olfaction
(01:00:12) Congenital Anosmia
(01:06:19) Handshaking, Sharing Chemicals & Social Sensing
(01:15:07) Smelling Ourselves & Smelling Others
(01:22:02) Odors & Romantic Attraction
(01:24:58) Vomeronasal Organ, “Bruce Effect” & Miscarriage
(01:40:20) Social Chemo-Signals, Fear
(01:50:26) Chemo-Signaling, Aggression & Offspring
(02:03:57) Menstrual Cycle Synchronization
(02:12:11) Sweat, Tears, Emotions & Testosterone
(02:27:46) Science Politics
(02:37:54) Food Odors & Nutritional Value
(02:45:34) Human Perception & Odorant Similarity
(02:52:12) Digitizing Smell, COVID-19 & Smell
(03:05:50) Medical Diagnostic Future & Olfaction Digitization
(03:10:55) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Disclaimer
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