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Tools for Hormone Optimization in Males | Dr. Kyle Gillett

Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. 
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

My guest is Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health. We discuss how to optimize male hormones using a range of nutritional and behavioral tools, exercise, and supplementation (including discussions on tongkat ali, fadogia agrestis, creatine, peptides and more). We explain how puberty and aging affect hormone levels, how to use bloodwork to monitor hormone levels, how hormone health impacts fertility, libido, hair loss, and prostate health, and describe behaviors that negatively impact testosterone levels. We also discuss how to approach prescription hormone therapies, including which biomarkers to monitor when using these approaches and how to optimize synergistic hormones (e.g., growth hormone and thyroid hormone) to support complete hormone health safely and rationally. Dr. Gillett offers numerous actionable tools that can be tailored to specific goals and age ranges to attain and maintain optimal levels of male hormones for overall health, well-being and longevity. 
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
Athletic Greens: https://athleticgreens.com/huberman
LMNT: https://drinklmnt.com/huberman
Momentous: https://www.livemomentous.com/huberman
Huberman Lab Premium
https://hubermanlab.com/premium
Timestamps
(00:00:00) Dr. Kyle Gillett & Male Hormone Optimization
(00:03:56) Sponsor: LMNT
(00:07:43) Puberty: Height, Resistance Training, Childhood Obesity
(00:15:14) “First” vs. “Second” Puberty
(00:17:17) Hormone Optimization & Blood Work
(00:22:14) Diet, Exercise, Sleep & Hormones
(00:28:23) Hormones, Stress, Social Connection & Purpose
(00:32:19) Hormones, Supplementation & Medication
(00:34:08) Determining Individual Hormone Levels, ADAM Questionnaire
(00:40:35) Libido, Masturbation, Pornography & the Dopamine “Wave Pool”
(00:47:56) Sponsor: AG1
(00:49:46) Sustainable Exercise Regimen for Hormone Health
(00:58:12) Testosterone Replacement Therapy (TRT)
(01:01:02) Supplementation: Creatine & Hair Loss, Betaine, L-Carnitine & Allicin (Garlic)
(01:11:45) Vitamin D, Boron; SHBG & Free Testosterone
(01:15:34) Sponsor: InsideTracker
(01:16:39) Tongkat Ali (Eurycoma longifolia; Longjack) & Steroid Pathways
(01:22:09) Fadogia Agrestis & Testosterone 
(01:26:32) Optimize Growth Hormone & IGF-1: Diet, Fasting, Supplements & Exercise 
(01:31:52) Optimize Thyroid Hormone: Iodine & Goitrogens
(01:33:56) Peptides: Growth Hormone, Tesamorelin, Ibutamoren & Gut Microbiome
(01:42:06) Testosterone Therapy
(01:47:03) Prescriptions & Hormones: Human Choriogonadotropin (HCG), Clomiphene
(01:52:56) Testosterone Therapy + HCG, Fertility & Temperature
(01:55:30) Hormone Health Q&A: Marijuana, Nicotine, Cycling, Pelvic Floor, Alcohol, Fat
(02:06:08) Prostate Health & Tadalafil, Prostate Specific Antigen (PSA)
(02:09:56) Hair Loss & DHT; Turmeric & Curcuminoids
(02:18:13) BPAs, Phthalates & Hormone Health
(02:21:55) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Momentous, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

My guest is Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health. We discuss how to optimize male hormones using a range of nutritional and behavioral tools, exercise, and supplementation (including discussions on tongkat ali, fadogia agrestis, creatine, peptides and more). We explain how puberty and aging affect hormone levels, how to use bloodwork to monitor hormone levels, how hormone health impacts fertility, libido, hair loss, and prostate health, and describe behaviors that negatively impact testosterone levels. We also discuss how to approach prescription hormone therapies, including which biomarkers to monitor when using these approaches and how to optimize synergistic hormones (e.g., growth hormone and thyroid hormone) to support complete hormone health safely and rationally. Dr. Gillett offers numerous actionable tools that can be tailored to specific goals and age ranges to attain and maintain optimal levels of male hormones for overall health, well-being and longevity. 
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1: https://athleticgreens.com/huberman
LMNT: https://drinklmnt.com/hubermanlab
Waking Up: https://wakingup.com/huberman
Momentous: https://livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Kyle Gillett & Male Hormone Optimization
(00:03:56) Sponsor: LMNT
(00:07:43) Puberty: Height, Resistance Training, Childhood Obesity
(00:15:14) “First” vs. “Second” Puberty
(00:17:17) Hormone Optimization & Blood Work
(00:22:14) Diet, Exercise, Sleep & Hormones
(00:28:23) Hormones, Stress, Social Connection & Purpose
(00:32:19) Hormones, Supplementation & Medication
(00:34:08) Determining Individual Hormone Levels, ADAM Questionnaire
(00:40:35) Libido, Masturbation, Pornography & the Dopamine “Wave Pool”
(00:47:56) Sponsor: AG1
(00:49:46) Sustainable Exercise Regimen for Hormone Health
(00:58:12) Testosterone Replacement Therapy (TRT)
(01:01:02) Supplementation: Creatine & Hair Loss, Betaine, L-Carnitine & Allicin (Garlic)
(01:11:45) Vitamin D, Boron; SHBG & Free Testosterone
(01:15:34) Sponsor: InsideTracker
(01:16:39) Tongkat Ali (Eurycoma longifolia; Longjack) & Steroid Pathways
(01:22:09) Fadogia Agrestis & Testosterone 
(01:26:32) Optimize Growth Hormone & IGF-1: Diet, Fasting, Supplements & Exercise 
(01:31:52) Optimize Thyroid Hormone: Iodine & Goitrogens
(01:33:56) Peptides: Growth Hormone, Tesamorelin, Ibutamoren & Gut Microbiome
(01:42:06) Testosterone Therapy
(01:47:03) Prescriptions & Hormones: Human Choriogonadotropin (HCG), Clomiphene
(01:52:56) Testosterone Therapy + HCG, Fertility & Temperature
(01:55:30) Hormone Health Q&A: Marijuana, Nicotine, Cycling, Pelvic Floor, Alcohol, Fat
(02:06:08) Prostate Health & Tadalafil, Prostate Specific Antigen (PSA)
(02:09:56) Hair Loss & DHT; Turmeric & Curcuminoids
(02:18:13) BPAs, Phthalates & Hormone Health
(02:21:55) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Momentous, Neural Network Newsletter
Disclaimer
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