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Life, Death & the Neuroscience of Your Unique Experience | Dr. David Linden

Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. 
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

In this episode, my guest is Dr. David Linden, Ph.D., professor of neuroscience at Johns Hopkins University School of Medicine and the author of many popular books about the brain. We discuss individual differences between people — focusing on differences in how people sense the world around them and the roles that chance, heredity, and life experiences (even in utero) play in determining our physical and cognitive traits. We discuss the bidirectional connection between the mind and body and how our thoughts and mental practices (e.g., meditation and breathwork) impact our health. We also discuss the link between inflammation and depression. We also discuss Dr. Linden’s terminal illness diagnosis, his mindset during chemotherapy and what his diagnosis has taught him about the mind, gratitude, time perception and life. This episode also covers sensual touch, cerebellar function, and epigenetic inheritance and ought to be of interest to all interested in neuroscience, genetics, psychology and human development. 
For the full show notes, including articles, books, and other resources, visit hubermanlab.com.
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Timestamps
(00:00:00) David Linden
(00:03:59) Sponsors: ROKA & Levels; Huberman Lab Survey
(00:07:54) Sensory Touch & Genitals, Krause Corpuscles
(00:16:46) Sexual Experiences & Sensation
(00:19:14) Human Individuality & Variation; Senses & Odor Detection
(00:30:25) Sponsor: AG1
(00:31:22) Visual Individuality; Heat Tolerance; Early Life Experiences & Variation
(00:40:28) Auditory Variability, Perfect Pitch
(00:42:08) Heritability & Human Individuality: Cognitive & Physical Traits
(00:49:36) Heritability, Environment, Personality; Twin Studies
(01:00:12) Sponsor: InsideTracker
(01:01:19) Development, Chance; Transgenerational Epigenetic Inheritance
(01:07:37) Single Generation Epigenetic Inheritance & Stress; Autism
(01:15:52) Sleep Paralysis; Cerebellum, Prediction
(01:23:47) Nature vs. Nature, Experience; Linden Hypothesis
(01:30:37) Mind-Body Interaction; Chemical Signals
(01:39:10) Inflammation & Depression
(01:43:35) Neuroplasticity, Inflammation & Mental Disorders; Microglial Cells, Exercise 
(01:52:15) Fads & Science
(01:55:16) Mind-Body Communication; Cancer 
(02:03:28) Mind-Body, Mediation, Breathwork
(02:07:30) Atrial Fibrillation, Synovial Sarcoma, Heart 
(02:14:22) Gratitude & Anger; Chemotherapy, Curiosity & Time Perception
(02:19:58) Death, Brain & Future Prediction, Religion & Afterlife
(02:24:15) Life Advice; Time Perception & Gratitude
(02:34:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

In this episode, my guest is Dr. David Linden, Ph.D., professor of neuroscience at Johns Hopkins University School of Medicine and the author of many popular books about the brain. We discuss individual differences between people — focusing on differences in how people sense the world around them and the roles that chance, heredity, and life experiences (even in utero) play in determining our physical and cognitive traits. We discuss the bidirectional connection between the mind and body and how our thoughts and mental practices (e.g., meditation and breathwork) impact our health. We also discuss the link between inflammation and depression. We also discuss Dr. Linden’s terminal illness diagnosis, his mindset during chemotherapy and what his diagnosis has taught him about the mind, gratitude, time perception and life. This episode also covers sensual touch, cerebellar function, and epigenetic inheritance and ought to be of interest to all interested in neuroscience, genetics, psychology and human development. 
For show notes, including referenced articles and additional resources, please visit hubermanlab.com.
Use Ask Huberman Lab, our new AI-powered platform, for a summary, clips, and insights from this episode.
Thank you to our sponsors
AG1: https://athleticgreens.com/huberman
LMNT: https://drinklmnt.com/hubermanlab
Waking Up: https://wakingup.com/huberman
Momentous: https://livemomentous.com/huberman
Timestamps
(00:00:00) David Linden
(00:04:15) Sponsors: LMNT & Waking Up
(00:07:54) Sensory Touch & Genitals, Krause Corpuscles
(00:16:46) Sexual Experiences & Sensation
(00:19:14) Human Individuality & Variation; Senses & Odor Detection
(00:29:32) Sponsor: AG1
(00:31:22) Visual Individuality; Heat Tolerance; Early Life Experiences & Variation
(00:40:28) Auditory Variability, Perfect Pitch
(00:42:08) Heritability & Human Individuality: Cognitive & Physical Traits
(00:49:36) Heritability, Environment, Personality; Twin Studies
(01:01:19) Development, Chance; Transgenerational Epigenetic Inheritance
(01:07:37) Single Generation Epigenetic Inheritance & Stress; Autism
(01:15:52) Sleep Paralysis; Cerebellum, Prediction
(01:23:47) Nature vs. Nature, Experience; Linden Hypothesis
(01:30:37) Mind-Body Interaction; Chemical Signals
(01:39:10) Inflammation & Depression
(01:43:35) Neuroplasticity, Inflammation & Mental Disorders; Microglial Cells, Exercise 
(01:52:15) Fads & Science
(01:55:16) Mind-Body Communication; Cancer 
(02:03:28) Mind-Body, Mediation, Breathwork
(02:07:30) Atrial Fibrillation, Synovial Sarcoma, Heart 
(02:14:22) Gratitude & Anger; Chemotherapy, Curiosity & Time Perception
(02:19:58) Death, Brain & Future Prediction, Religion & Afterlife
(02:24:15) Life Advice; Time Perception & Gratitude
(02:34:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Disclaimer
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