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#153 – Dmitry Korkin: Evolution of Proteins, Viruses, Life, and AI

Lex Fridman Podcast

Conversations that explore technology, history, philosophy, physics, mathematics, biology, chemistry, engineering, AI, robotics, programming, music, film, art, sports, psychology, neuroscience, geopolitics, business, economics, religion, astronomy, and the human condition with people from all walks of life.

Dmitry Korkin is a professor of bioinformatics and computational biology at WPI. Please support this podcast by checking out our sponsors:
- Brave: https://brave.com/lex
- NetSuite: http://netsuite.com/lex to get free product tour
- Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off
- Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get special savings

EPISODE LINKS:
Dmitry's Website: http://korkinlab.org/
Dmitry's Twitter: https://twitter.com/dmkorkin

PODCAST INFO:
Podcast website: https://lexfridman.com/podcast
Apple Podcasts: https://apple.co/2lwqZIr
Spotify: https://spoti.fi/2nEwCF8
RSS: https://lexfridman.com/feed/podcast/
YouTube Full Episodes: https://youtube.com/lexfridman
YouTube Clips: https://youtube.com/lexclips

SUPPORT & CONNECT:
- Check out the sponsors above, it's the best way to support this podcast
- Support on Patreon: https://www.patreon.com/lexfridman
- Twitter: https://twitter.com/lexfridman
- Instagram: https://www.instagram.com/lexfridman
- LinkedIn: https://www.linkedin.com/in/lexfridman
- Facebook: https://www.facebook.com/LexFridmanPage
- Medium: https://medium.com/@lexfridman

OUTLINE:
Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.
(00:00) - Introduction
(07:21) - Proteins and the building blocks of life
(14:23) - Spike protein
(21:11) - Coronavirus biological structure explained
(26:09) - Virus mutations
(32:39) - Evolution of proteins
(42:25) - Self-replicating computer programs
(50:02) - Origin of life
(57:34) - Extraterrestrial life in our solar system
(59:31) - Joshua Lederberg
(1:05:30) - Dendral
(1:08:24) - Why did expert systems fail?
(1:10:35) - AlphaFold 2
(1:32:13) - Will AI revolutionize art and music?
(1:39:12) - Multi-protein folding
(1:43:39) - Will AlphaFold 2 result in a Nobel Prize?
(1:46:10) - Will AI be used to engineer deadly viruses?
(2:01:17) - Book recommendations
(2:11:00) - Family
(2:13:38) - A poem in Russian

Dmitry Korkin is a professor of bioinformatics and computational biology at WPI. Please support this podcast by checking out our sponsors: 
– Brave: <a href="https://brave.com/lex">https://brave.com/lex</a> 
– NetSuite: <a href="http://netsuite.com/lex">http://netsuite.com/lex</a> to get free product tour 
– Magic Spoon: <a href="https://magicspoon.com/lex">https://magicspoon.com/lex</a> and use code LEX to get $5 off 
– Eight Sleep: <a href="https://www.eightsleep.com/lex">https://www.eightsleep.com/lex</a> and use code LEX to get special savings
EPISODE LINKS: 
Dmitry’s Website: <a href="http://korkinlab.org/">http://korkinlab.org/</a> 
Dmitry’s Twitter: <a href="https://twitter.com/dmkorkin">https://twitter.com/dmkorkin</a>
PODCAST INFO: 
Podcast website: <a href="https://lexfridman.com/podcast">https://lexfridman.com/podcast</a> 
Apple Podcasts: <a href="https://apple.co/2lwqZIr">https://apple.co/2lwqZIr</a> 
Spotify: <a href="https://spoti.fi/2nEwCF8">https://spoti.fi/2nEwCF8</a> 
RSS: <a href="https://lexfridman.com/feed/podcast/">https://lexfridman.com/feed/podcast/</a> 
YouTube Full Episodes: <a href="https://youtube.com/lexfridman">https://youtube.com/lexfridman</a> 
YouTube Clips: <a href="https://youtube.com/lexclips">https://youtube.com/lexclips</a>
SUPPORT & CONNECT: 
– Check out the sponsors above, it’s the best way to support this podcast 
– Support on Patreon: <a href="https://www.patreon.com/lexfridman">https://www.patreon.com/lexfridman</a> 
– Twitter: <a href="https://twitter.com/lexfridman">https://twitter.com/lexfridman</a> 
– Instagram: <a href="https://www.instagram.com/lexfridman">https://www.instagram.com/lexfridman</a> 
– LinkedIn: <a href="https://www.linkedin.com/in/lexfridman">https://www.linkedin.com/in/lexfridman</a> 
– Facebook: <a href="https://www.facebook.com/LexFridmanPage">https://www.facebook.com/LexFridmanPage</a> 
– Medium: <a href="https://medium.com/@lexfridman">https://medium.com/@lexfridman</a>
OUTLINE: 
Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. 
(00:00) – Introduction 
(07:21) – Proteins and the building blocks of life 
(14:23) – Spike protein 
(21:11) – Coronavirus biological structure explained 
(26:09) – Virus mutations 
(32:39) – Evolution of proteins 
(42:25) – Self-replicating computer programs 
(50:02) – Origin of life 
(57:34) – Extraterrestrial life in our solar system 
(59:31) – Joshua Lederberg 
(1:05:30) – Dendral 
(1:08:24) – Why did expert systems fail? 
(1:10:35) – AlphaFold 2 
(1:32:13) – Will AI revolutionize art and music? 
(1:39:12) – Multi-protein folding 
(1:43:39) – Will AlphaFold 2 result in a Nobel Prize? 
(1:46:10) – Will AI be used to engineer deadly viruses? 
(2:01:17) – Book recommendations 
(2:11:00) – Family 
(2:13:38) – A poem in Russian

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#153 – Dmitry Korkin: Evolution of Proteins, Viruses, Life, and AI

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