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#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics

Lex Fridman Podcast

Conversations about science, technology, history, philosophy and the nature of intelligence, consciousness, love, and power. Lex is an AI researcher at MIT and beyond.

Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group. He is interested in understanding the human genome from a computational, evolutionary, biological, and other cross-disciplinary perspectives.

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Here's the outline of the episode. On some podcast players you should be able to click the timestamp to jump to that time.

OUTLINE:
00:00 - Introduction
03:54 - Human genome
17:47 - Sources of knowledge
29:15 - Free will
33:26 - Simulation
35:17 - Biological and computing
50:10 - Genome-wide evolutionary signatures
56:54 - Evolution of COVID-19
1:02:59 - Are viruses intelligent?
1:12:08 - Humans vs viruses
1:19:39 - Engineered pandemics
1:23:23 - Immune system
1:33:22 - Placebo effect
1:35:39 - Human genome source code
1:44:40 - Mutation
1:51:46 - Deep learning
1:58:08 - Neuralink
2:07:07 - Language
2:15:19 - Meaning of life

Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group. He is interested in understanding the human genome from a computational, evolutionary, biological, and other cross-disciplinary perspectives.
Support this podcast by supporting our sponsors: 
– Blinkist: <a href="https://blinkist.com/lex">https://blinkist.com/lex</a> 
– Eight Sleep: <a href="https://eightsleep.com/lex">https://eightsleep.com/lex</a> 
– MasterClass: <a href="https://masterclass.com/lex">https://masterclass.com/lex</a>
If you would like to get more information about this podcast go to <a href="https://lexfridman.com/ai">https://lexfridman.com/ai</a> or connect with @lexfridman on <a href="https://twitter.com/lexfridman">Twitter</a>, <a href="https://www.linkedin.com/in/lexfridman/">LinkedIn</a>, <a href="https://www.facebook.com/lexfridman">Facebook</a>, <a href="https://medium.com/@lexfridman">Medium</a>, or <a href="https://www.youtube.com/lexfridman">YouTube</a> where you can watch the video versions of these conversations. If you enjoy the podcast, please rate it 5 stars on <a href="https://podcasts.apple.com/us/podcast/artificial-intelligence/id1434243584">Apple Podcasts</a>, follow on <a href="https://open.spotify.com/show/2MAi0BvDc6GTFvKFPXnkCL">Spotify</a>, or support it on <a href="https://www.patreon.com/lexfridman">Patreon</a>.
Here’s the outline of the episode. On some podcast players you should be able to click the timestamp to jump to that time.
OUTLINE: 
00:00 – Introduction 
03:54 – Human genome 
17:47 – Sources of knowledge 
29:15 – Free will 
33:26 – Simulation 
35:17 – Biological and computing 
50:10 – Genome-wide evolutionary signatures 
56:54 – Evolution of COVID-19 
1:02:59 – Are viruses intelligent? 
1:12:08 – Humans vs viruses 
1:19:39 – Engineered pandemics 
1:23:23 – Immune system 
1:33:22 – Placebo effect 
1:35:39 – Human genome source code 
1:44:40 – Mutation 
1:51:46 – Deep learning 
1:58:08 – Neuralink 
2:07:07 – Language 
2:15:19 – Meaning of life

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#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics

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